2025 has emerged as a pivotal moment for healthcare transformation, with 4.5 billion people currently lacking access to essential healthcare services and AI offering potential to bridge at least a portion of that gap. Healthcare startups are responding with AI-driven solutions, with AI-focused startups capturing 62% of all digital health venture funding in the first half of 2025, raising $3.95 billion and commanding an 83% premium over non-AI peers.
Healthcare startups are driving rapid AI adoption among providers, with digital health companies raising $6.4 billion in the first three quarters of 2025 and the sector witnessing promising exit activity through IPOs and M&A deals. Digital platforms are evolving to deliver AI-driven patient throughput that streamlines workflows, integrates data, and guides patients to optimal care settings, reducing administrative burdens while enhancing clinical decision-making.
Healthcare organizations are now moving beyond the hype to focus on AI applications that deliver demonstrable value and real-world impact in patient care and clinical workflows. These innovations converge with personalized medicine solutions and automated provider workflows creating resilient healthcare ecosystems capable of adapting to demographic volatility while maintaining quality care at scale.
Capita3 Annual Meeting Highlights
We held our 2025 annual meeting earlier this month and were pleased to be joined by portfolio companies Flourish, FlyteHealth, Claros and b.well. As usual, the company presentations the highlight of the day. Thank you to our LPs, Portfolio company presenters and sponsors JP Morgan, Husch Blackwell and Baker Tilly for their support of us and our portfolio.
Portfolio Company Updates
We are excited to share our most recent investment in the company in Flourish Care, a tech enabled maternal healthcare service company delivering unparalleled doula care. See our announcement here
Claros successfully demonstrated high throughput PFAS destruction in pilot. Daikin America Inc.’s
Claros also closed on a $10M financing with existing and new investors, positioning the company for growth as they head into 1H2025 and beyond.
Persephone launched their first products, Bloom and Thrive with a >10,000 family waitlist on launch day. See our announcement here. Persephone also published their study that found most U.S. babies lack key gut bacteria, increasing risk for allergies and other chronic health issues.
NextSense launched their first product, SmartBuds. See our announcement here.
SmartBuds are the first truly wireless earbuds that actually tune in to your brain’s rhythm in real time, helping you experience deeper rest, sharper focus, and that all-important sense of being fully present.
FlyteHealth announced new CEO, Cheryl Pagasus. The Company is also expanding its reach and enhancing patient outcomes through a strategic partnership with Heartbeat Health. Together, they will deliver seamless, integrated cardiometabolic and cardiovascular care,
Paterna recently completed the Mayo accelerator. The Mayo Clinic and Arizona State University program offers a hands-on entrepreneurial curriculum and tailored business development plans, designed to help participants bring their ideas to market and connect with investment opportunities faster.
We're proud to announce that Capita3 has been selected to participate in the 2025 RAISE Global Summit, the premier gathering for emerging venture capital managers and forward-thinking limited partners. This highly selective, invite-only event brings together just 101 emerging fund managers with more than 330 leading LPs at The Presidio in San Francisco.
Being selected for RAISE represents a significant milestone in our journey.
The rigorous selection process, overseen by a distinguished committee of limited partners, recognizes Capita3 among the next generation of innovative VC firms. We look forward to connecting with institutional investors, family offices, and fellow fund managers who are shaping the future of venture capital, while showcasing the unique value proposition we bring to our portfolio companies and partners.
We're thrilled to announce that Capita3 has been selected for VC Include's Cohort V, the fifth annual Fellowship for Impact Fund I Managers. This prestigious program brings together just 16 exceptional first-time fund managers representing 13 venture and real estate funds, chosen through a rigorous and highly competitive selection process from emerging managers across the country.
VC Include's Fellowship is designed to educate the next generation of institutional-grade asset managers in venture capital, private equity, and impact investing. As part of Cohort V, we join a distinguished community of 75+ Fellowship alumni who have collectively raised over $1 billion in assets, backed hundreds of companies, and created thousands of jobs.
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